Biochemical and Physical Changes in Shaken Suspensions of Pasteurella pestis

Stability of cell suspensions of Pasteurella pestis at 5 C and at -23 C.

Viability of Airborne Pasteurella pestis

WON, WILIAiM D. (University of Caifornia, Berkeley), ANm HAROLD Ross. Effect of diluent and relative humidity on apparent viability of airborne Pasteurella pestis. Appl. Microbiol. 14:742-745. 1966.-Airborne Pasteurella pestis (A-1122) at low humidities [20 to 50% relative humidity (RH)] exhibited exponential decay when either 1% peptone or Heart Infusion Broth (HIB) was used as the diluent in ...

Production of Pasteurella pestis toxin.

In the course of the development of a casein hydrolyzate mineral glucose medium for the growth of Pasteurella pestis, strain A1122, for the production of the envelope antigen (Englesberg and Levy, 1954), the potential use of this medium for plague toxin production became apparent. The development of a simplified method for the production of plague toxin made possible by this medium will be desc...

Interconversion of Purine Mononucleotides in Pasteurella pestis.

Included among the five established determinants of virulence in Pasteurella pestis are the abilities of cells to accomplish the de novo biosynthesis of purines and to grow as dark pigmented (P(+)) colonies on a solid synthetic medium containing hemin. P(+) isolates of P. pestis strain KIM-10 (mouse intraperitoneal ld(50) < 10 cells) failed to convert exogenous guanine-8-(14)C to adenine residu...

Infectivity and virulence of nonpesticinogenic Pasteurella pestis.

Nonpesticinogenic Pasteurella pestis, which is also negative for coagulase and fibrinolytic activities and therefore referred to as (PI-C-F)(-), was investigated to determine whether greatly reduced and erratic lethal responses observed in mice and guinea pigs might be due to inability of the inoculum to establish infection and multiply in survivors. Immunity of survivors was regarded as an ind...